bFGF
Basic Fibroblast Growth Factor (bFGF) is a multipotent cell growth factor that acts extensively on tissues and cells of mesodermal and neuroectodermal origin. Its basic biological role is to promote cell division and proliferation. Another important function of bFGF is its pro-angiogenic effect. It can rapidly generate new blood vessels in corneal, skin and renal peritoneal tissues; it can chemotacticize various types of cells in the endothelium and stimulate their proliferation and migration, thus playing an important role in tumor development and tissue repair of atherosclerotic plaque damage. bFGF is also a neurotrophic factor, which has a role in promoting the growth and differentiation of neural tissues and maintaining their survival. bFGF has an important role in the induction of embryonic development. Normal embryonic development depends heavily on the induction of the mesoderm. bFGF can act on a variety of cells from the mesoderm and participate in the induction of the mesoderm. There are many experiments that confirm that bFGF can inhibit apoptosis.